abstract |
The present invention relates to a novel amlodipine camsylate salt and a method for preparing the same. Specifically, the amlodipine may be selected from (1S)-(+)-10-camphorsulphonic acid, (1R)-(-). Novel amlodipine camsylate of Formula 1, a crystalline acid addition salt with excellent physicochemical properties such as solubility, stability, non-hygroscopicity and tablet adhesion, prepared by reacting with -10-campo sulfonic acid or (±) -10-campo sulfonic acid A salt and a method for preparing the same The amlodipine camsylate salt according to the preparation method of the present invention can be usefully used as a pharmaceutical composition for treating cardiovascular diseases because of its low toxicity and low toxicity compared to conventional amlodipine acid addition salts. |