| abstract |
The present invention relates to an indazole compound that modulates or inhibits cell proliferation due to the activity of protein kinases. The indazole compound and pharmaceutical composition can modulate kinase-dependent diseases that regulate or inhibit unwanted cell proliferation. In the present invention, direct therapy or prophylaxis using the pharmaceutical composition of the compound and an effective amount of the compound are administered to prevent unwanted effects such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis and psoriasis. A number of other diseases associated with angiogenesis and / or cell proliferation are proposed as well as methods for treating cancer. |