abstract |
The present invention relates to a compound of formula (1) or a pharmaceutically acceptable salt thereof useful as an inhibitor of PDE4 in the treatment of diseases regulated by activation and degranulation of eosinophils, in particular asthma, chronic bronchitis and chronic obstructive pulmonary disease. In Formula 1, R 5 and R 6 are bonded together to form a residue of Formulas (1.1.1) to (1.1.5).n n n Formula 1 |