http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020070565-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b3be70086419df7430dcf0abc1da93 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-192 |
filingDate | 2001-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f7f0f4e53727b61c9f44bb16cdb9b8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e841a9307a82fa7ba83fa1b42f9ab3c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_397747377e9b72d09ab9e6b7bc38434e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dd2afee69efe6544c47e7c81416b60e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1250caa7d7cbfdbecd260cd4065ca6e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53e779d20099b2305458f19a660324ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c27a12a7295e1b93a8e1f74305e95d4 |
publicationDate | 2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20020070565-A |
titleOfInvention | Novel α-keto amide derivatives and process for preparing the same |
abstract | The present invention provides a novel α-ketoamide derivative of formula (1) having a inhibitory effect on phosphodiesterase IV and tumor necrosis factor (TNFα), and a pharmaceutically acceptable salt and solvate thereof, and a method for preparing the same. It relates to pharmaceutical compositions containing them:n n n [Formula 1]n n n n n n n n Wheren n n R 1 and R 1 ′ are the same as or different from each other and represent H, OH or OR 2 , wherein R 2 represents a (C 1 -C 7 ) alkyl group, (C 3 -C 7 ) cycloalkyl group or Bn,n n n R 3 represents hydrogen,n n n R 4 is , Orn n n R 3 and R 4 together with the nitrogen atom to which they are attached, Can form a heterocyclic ring,n n n From here,n n n X and Y are the same as or different from each other, and represent a hydrogen atom or a halogen atom,n n n Z represents CH or N,n n n A represents a CH 2 , S, O or NR 5 element, wherein R 5 represents H or a (C 1 -C 7 ) alkyl group,n n n n represents the number of 1-3. |
priorityDate | 2001-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.