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filingDate 2001-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2002-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20020069437-A
titleOfInvention 4-hydroxyphenylglycine anhydrides and process for the preparation thereof
abstract The present invention relates to 4-hydroxyphenylglycine anhydrides of formula (1) which can be used as intermediates in the preparation of oral cephalosporin-based antibiotics, and to a preparation method thereof. According to the method of the present invention, which comprises reacting pivaloyl halide in the presence of a base, 4-hydroxyphenylglycine anhydride of formula (1) can be easily prepared, which can be used to prepare oral cephalosporin antibiotics. It is very useful as an intermediate.n n n n n n n n n n In the formula, R means amino protecting group.
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