abstract |
The present invention is a 2,3-di-substituted compound of formula I, which is a glucokinase activator that increases insulin in the treatment of type II diabetes, wherein the 2-position is substituted with a phenyl group and the 3-position is substituted with a cycloalkyl ring. Trans olefin N-heteroaromatic or we also relates to propionamide:n n n Formula I |