| abstract |
The present invention provides a method of treating a disease or disorder responsive to the inhibition of nuclear factor-κB transcription factors comprising administering a sulfonylaminocarbonyl derivative, or a pharmaceutically acceptable salt thereof, to a subject in need thereof. The method of the present invention includes, for example, rheumatoid arthritis, osteoarthritis, autoimmune diseases, psoriasis, asthma, cardiovascular disease, acute coronary syndrome, congestive heart failure, Alzheimer's disease, multiple sclerosis, cancer, type 2 diabetes, metabolic syndrome Useful for the treatment of X, or inflammatory bowel disease. |