Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-44 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
1999-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2002-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20020064886-A |
titleOfInvention |
Expression of Recombinant Mature Lysostaphin |
abstract |
A portion of the resource tagine gene of Staphylococcus simulans is cloned and ligated to the IPTG-inducible promoter and ribosome binding site under transcriptional control. Was overexpressed in the cytoplasm of E. coli to obtain mature resource taktins without pre-pro-resource tapin and pro-resource tapkin. IPTG induction of transformed host cells produces intracellular soluble mature resource taktins (27 kDa) free of preprytorapin and protonatopin. The mature resource tarpaulin thus formed does not require post-translational modification. The mature resource taprin thus formed can be used for the treatment and prevention of staphylococcus infection. |
priorityDate |
1999-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |