| abstract |
The present invention relates to a heterocyclic compound of formula (I) used as a medicament having an inhibitory effect on AP-1 activity, NF-Kappa B activity, inflammatory cytokine production, matrix metalloprotease production, inflammatory cell adhesion factor expression, and the like. .n n n Formula In n n n n n n n In Formula I above,n n n R 1 is cycloalkyl or cycloalkenyl,n n n R 2 and R 3 are each hydrogen or alkyl,n n n R 4 is alkyl, heterocycle,n n n n is an integer from 0 to 6,n n n A is a heterocycle,n n n B is an aromatic ring or heterocycle,n n n X and Y are each a bonding or linking group. |