| abstract |
Novel compounds (II) which are potent and selective inhibitors of PDE4 as well as methods for their preparation are described. Also disclosed is the use of this compound for the treatment of central nervous system (CNS) diseases as well as other diseases associated with increasing infectious diseases and cytokine concentrations. R 1 -R 7 , R 10 and R 12 are described in the specification.n n n [Formula II] |