| abstract |
Claims 1. Compounds of the formula < RTI ID = 0.0 > I < / RTI &n n n (I)n n n n n n n n R 1 and R 2 are independently hydrogen, fluorine or alkyl, R 3 is aryl or heteroaryl, R 4 has various meanings, and the symbols used throughout the specification have the following meanings: R 5 is hydrogen or alkyl, m is an integer from 0 to 2, and n is an integer from 1 to 3.n n n The compounds of formula I are protein kinase inhibitors and are useful in the treatment and prophylaxis of proliferative diseases such as cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease, cardiovascular diseases, viral diseases and fungal diseases. |