http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020048927-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-29 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-29 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-04 |
filingDate | 2000-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20020048927-A |
titleOfInvention | Hydroxylation of compactin to pravastatin by micromonospora |
abstract | The present invention relates to a process for the production of a product of the formula (I) which is formed during aerobic fermentation by culturing a strain capable of 6? -Hydroxylation of the compound of the formulan n n Formula In n n n n n n n The compound of the formula (II) < RTI ID = 0.0 >n n n (II)n n n n n n n n To a novel method for microbially producing a compound of formula (I). The latter separation purification method comprises the following steps:n n n a) cultivating a micro-monospore strain capable of 6? -hydroxylation of a compound of formula (II) (wherein R is as defined above) on an ordinary medium containing available carbon sources, nitrogen sources and mineral salts at 25-32 ° C next ;n n n b) adding the substrate to transform into the developed culture;n n n c) hydrolyzing the substrate until the end of bioconversion;n n n d) separating the compound of formula (I) from the culture broth and purifying it if necessary. |
priorityDate | 1999-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 370.