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filingDate 2001-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78eada947fa6f4d2ee96054a9a66870
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publicationDate 2002-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20020046200-A
titleOfInvention Anti-abnormal type prion monoclonal antibody, process for producing the same, and immunoassay using the same
abstract A monoclonal antibody capable of distinguishing an abnormal prion from a normal prion, and a preparation method thereof are disclosed. Anti-amorphous prion monoclonal antibodies of the present invention react with an abnormal prion by antigen-antibody reactions but do not substantially react with normal prions by antigen-antibody reactions. The anti-amorphous prion monoclonal antibodies of the present invention can be obtained by immunizing an animal with an immunogen comprising a peptide containing a plurality of regions that are discontinuously present in each other in the primary amino acid sequence of the abnormal prion.
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