| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b1b54f50a3ca3323f279860b5382c2d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N31-226
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-22 |
| filingDate |
2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a6bf2e410c0479ea1284914d59a064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce1245e6186c7fede1c6ae4cac181076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aacdeb4417895104dac30f9b2fe6ea9 |
| publicationDate |
2002-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20020033080-A |
| titleOfInvention |
Biological indicator for sterilization processes with double buffer system |
| abstract |
The present invention relates to a method and apparatus for preventing the return of indicator dye color in a biological indicator. The indicator dye changes color because, after sterilization, when viable microbes are present, they produce acid by-products when the microbes metabolize the growth medium. By the present application, it has been observed that the color returns to the original color after completion of sterilization due to leaching or diffusion of basic impurities into the growth medium. The method and apparatus of the present invention employ a dual buffer system containing a first buffer that acts at high pH to mitigate pH variation at the start of sterilization and a second buffer that acts at low pH to minimize pH variation after completion of sterilization. High pH buffers are used in smaller amounts than low pH buffers to maximize the speed and sensitivity of the biological indicators. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015137625-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208329-B2 |
| priorityDate |
2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |