http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020031601-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-42 |
| filingDate | 2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20020031601-A |
| titleOfInvention | Method for producing substituted phenylsulfonyl carbamides from sulfohalogenides |
| abstract | The present invention,n n n (a) ammonolysis of compound (II) in which Hal is a halogen atom, to give compound (III), preferably (a1) (1) an optionally halogenated aromatic hydrocarbon [solvent (1)], and (2 ) This reaction is carried out in an organic solvent mixture comprising a polar aprotic solvent [solvent (2)] in a solvent (1): solvent (2) weight ratio of 20: 1 to 1: 1,n n n (b) phosgenating compound (III) with phenylsulfonyl isocyanate of formula (IV), and preferably (b1) when X * is halogen, formula (R 1 -NCO) wherein R 1 is Reaction with phosgene in an organic solvent, with or without an amine base, in the presence of an isocyanate)n n n (c) reacting the resulting compound (IV) with an aminoheterocycle H 2 N-Het in which Het is a heterocycle as in (I) to give compound (I) or a salt thereof, Preferably this reaction is carried out in a solvent mixture of an optionally halogenated aromatic hydrocarbon with a boiling point above 110 ° C. and a polar aprotic solvent, one of the preferred partial steps (a1), (b1) and (c1). The present invention relates to a process for preparing a compound of formula (I) or a salt thereof:n n n Formula In n n n n n n n n n n n n n n Wheren n n Q, X * , Y, Z, R, R 1 , R 2 and R 3 are as defined in claim 1,n n n In formula VI, when R * is -Hal and formula II, when R * is -NH 2, and the formula III, if R * is a -NCO Formula IV. |
| priorityDate | 1999-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.