| abstract |
The present invention relates to a diacylhydrazine derivative of formula (I), a physiologically acceptable salt or solvate thereof, which is an integrin inhibitor and is a thrombosis, myocardial infarction, coronary heart disease, atherosclerosis, inflammation, tumor, osteoporosis, infection and It may be used to combat restenosis after angiogenesis or during pathological processes maintained or proliferated by angiogenesis:n n n [Formula I]n n n n n n n n [Wherein X, Y, Z, R 1 , R 2 and R 3 have the meanings recited in claim 1]. |