http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020016381-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
filingDate | 2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43920fe0e0e0dff96d530b46ef39dc20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4987b12e81584d827ad006630395cbf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3851bb46727c3d983c4990a42664a89e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_311116cdefb1b18576da9aeb20178b0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca2b29f66b2efc78e916485ab5cfdf28 |
publicationDate | 2002-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20020016381-A |
titleOfInvention | Novel 1β-Methylcarbapenem derivatives having 5'-heteroarylthiomethylpyrrolidin-3'-ylthio group and process for preparation thereof |
abstract | The present invention relates to a novel 1-betamethylcarbapenem derivative useful as an antimicrobial agent, a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for an antimicrobial agent comprising the same. 1-betamethylcarbapenem derivatives substituted with 5'-heteroarylthiomethylpyrrolidine-3'-ylthio group as the main functional group at position 1 show excellent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria and are dihydropeptides. It is stable against the first-I and has excellent intracellular bioavailability, and thus can be usefully used as an antibacterial agent.n n n n n n n n n n In Formula 1, R is as described in the specification. |
priorityDate | 2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.