| abstract |
The present invention relates to a bicyclic heterocycle of formula (I), its teomers, stereoisomers and salts, especially pharmacologically acceptable salts with inorganic or organic acids or bases.n n n Formula In n n n n n n n In the above formula (I)n n n R a , R b , R c , A, B, C, D, E and X are as defined in claim 1.n n n The non-cyclic heterocycle of the present invention has useful pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases.n n n The invention also relates to the use of the bicyclic heterocycle of the invention for the treatment of diseases, in particular of tumor diseases, lung and bronchial diseases, and to a process for the preparation of the compounds of the invention. |