abstract |
The present invention is directed to a series of novel monosubstituted and disubstituted 3-propyl gamma aminobutyric acids of the general formula (I) The compounds of the present invention are useful as therapeutic agents in the treatment of epilepsy, stroke, motor hypotonia, cranial diseases, neurodegenerative diseases, depression, anxiety, panic disorder, pain, neuropathological diseases, arthritis, sleep disorders, IBS and gastric injuries . Methods of making the compounds of the invention and useful intermediates are also part of the present invention.n n n ≪ Formula 1 > |