http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020003738-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2afec86507fc41d4fd24a6693763f876 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 |
| filingDate | 2000-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f83f3421440d448a6dd01395d7d63fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5af25b787eb94df28c02af5b9d3f7d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d52d8cd8f20f12d0d9600bcc66558d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc8065ae8c382c4cd1112486b7026ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b45c05dc98ab0b0bba508fd43ca9665 |
| publicationDate | 2002-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20020003738-A |
| titleOfInvention | A biocompatible and biodegradable sustained-release polymer matrix containing a hydrophilic drug or salt thereof |
| abstract | The present invention relates to a sustained release biodegradable polymer matrix containing a drug in the form of a hydrophilic or salt, the preparation method is PLGA (poly ( d, l -lactide-co-glycolide)), PGA (polyglycolide) A first step of dissolving the first polymer selected from the group consisting of PLA (polylactide), PEG (polyethylene glycol) second polymer and a surfactant in an organic solvent; Dissolving the drug in the form of a hydrophilic or salt in water; A third step of preparing a water in oil (W / O) emulsion by stirring the aqueous solution prepared by the second step into the organic solvent prepared by the first step; And a fourth step of removing water and an organic solvent. The polymer matrix prepared according to the invention is to increase the release rate of the drug and to improve the initial burst effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100540035-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102572527-B1 |
| priorityDate | 2000-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.