| abstract |
The present invention relates to compounds of formula (I) and to medicaments:n n n n n n n n Wheren n n R 1 , R 2 , R 3 and R 4 are independently hydrogen atom, halogen atom, or alkyl, alkoxy, hydroxy, cyano, optionally substituted amino, nitro, carboxy, alkoxycarbonyl, optionally substituted amino Carbonyl or carbonyl group,n n n L 1 and L 2 each represent a hydrogen atom or combine together to form a -CH 2 -CH 2 -group,n n n X 1 bonded to the 2 or 3 position of the aromatic ring represents a single bond, in which case X 2 represents a hydrogen atom, a halogen atom or an alkyl, alkoxy, hydroxy, nitro, cyano or optionally substituted amino group Or X 1 and X 2 combine with two adjacent carbon atoms to which they are bonded at the 2, 3 or 4 position of the aromatic ring to form a (C 4 -C 7 ) cycloalkyl group, wherein one of the cycloalkyl rings Or two-CH 2 -groups are optionally substituted by an oxygen atom or an NH group,n n n X 3 represents a hydrogen, a halogen atom or an alkyl, alkoxy, hydroxy, nitro, cyano or optionally substituted amino group,n n n G represents a group selected from the following formula:n n n n n n n n Wheren n n The dashed line represents an optionally present double bond,n n n Alk represents a linear or branched (C 1 -C 6 ) alkylene group,n n n n is 0 or 1,n n n T 3 represents an alkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl or optionally substituted heteroarylalkyl group,n n n T 4 represents an alkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl or optionally substituted heteroarylalkyl group. |