| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcd81592bb96512c68d5123a96f5a29f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0021 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 |
| filingDate |
2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ecb94392f0c1e0cd7628c0f3558a671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29aab3618ab476f26a2dd54dc8a00071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42dea53d4b4f1b2f1f6ccd2207aea1e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7da1e12e3867bcc59e96cd34c5124f74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03687a620bdc62eb92aac81c5e9cb054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e42c3f829a8c9eff22804eab4e2ab9a2 |
| publicationDate |
2002-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20020000227-A |
| titleOfInvention |
Carrier specific to liver cell and the carrier-DNA conujugate |
| abstract |
The present invention relates to a cationic polymer compound (GCD) carrier prepared by introducing dextran for improving stability in aqueous solution and galactose group specifically binding to the sialoglycol protein receptor of hepatocytes to chitosan, and a complex of the carrier and DNA. It is about. The GCD / DNA complex was transfected only in human liver cells and Hep G2 cells with the presence of asialoglycoprotein receptors on the cell surface, indicating that there is a specific interaction between the ASGR of the cell and the ligand of the chitosan. Means. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100718077-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011017930-A1 |
| priorityDate |
2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |