http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020000178-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20020000178-A |
| titleOfInvention | Use of biodegradable microspheres that release an anticancer agent for treating glioblastoma |
| abstract | The present invention relates to the use of biodegradable centroids for the release of radiation-sensitive anticancer agents for the manufacture of drugs which are intended to be used simultaneously, alone or over time for the treatment of gliomas. Use of the biodegradable centrosomes of the present invention results in patient survival time of at least 90 weeks, and therapeutically effective concentrations are maintained in the parenchymal space over this period. The core preferably contains 5-fluorouracil coated with poly (d, l-lactic acid-co-glycolic acid). The centrosome is implanted into the wall of the surgical site after excision of the tumor by in vivo injection. Radiation therapy targeting the tumor mass is irradiated at 60 Gy over about six weeks. The invention also relates to a process for preparing biodegradable centroids by emulsion-extraction and to suspensions containing the biodegradable centroids obtained using the method. |
| priorityDate | 1999-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 118.