http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20010113784-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate | 2000-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20010113784-A |
titleOfInvention | Camptothecin analogs and method of preparation thereof |
abstract | The compound has the structural formula (1), which is a racemic form, an enantiomerically enriched form or an enantiomerically pure form. R 6 is preferably -Si (R 8 R 9 R 10 ) or - (R 7 ) Si (R 8 R 9 R 10 ), wherein R 7 is an alkylene, alkenylene or alkynylene group and R 8 , R 9 and R 10 are independently a C 1-10 alkyl group, a C 2-10 alkenyl group, a C 2-10 alkynyl group, an aryl group, or - (CH 2 ) N R 11 wherein N is an integer of 1-10 And R 11 is a hydroxy group, an alkoxy group, an amino group, an alkylamino group, a dialkylamino group, a halogen atom, a cyano group, SR c or a nitro group. R1-R4 may be widely substituted. R 5 is preferably a C 1-10 alkyl group, an alkenyl group, an alkynyl group or a benzyl group. Preferably, R 13 is H, F or -CH 3. R 16 is -C (O) R f or H. The E-ring (lactone ring) can be opened. A method for synthesizing the compound (1) and intermediates in the synthesis thereof. |
priorityDate | 1999-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.