abstract |
The compounds of formula (I) or salts thereof have good Gn-RH antagonistic activity and are useful for the prevention or treatment of sex hormone dependent diseases:n n n [Formula I]n n n n n n n n [Wherein, R 1 and R 2 each represent a hydrogen atom, a hydroxy group, a C 1-4 alkoxy group, a C 1-4 alkoxy-carbonyl group or a C 1-4 alkyl group which may be substituted; R 3 represents a hydrogen atom, a halogen atom, a hydroxy group or a C 1-4 alkoxy group which may be substituted; Or two adjacent R 3 together may form a C 1-4 alkylenedioxy group; R 4 represents a hydrogen atom or a C 1-4 alkyl group; R 6 represents a C 1-4 alkyl group which may be substituted or a group of formula A:n n n [Formula A]n n n n n n n n (Wherein R 5 represents a hydrogen atom or R 4 and R 5 together may form a heterocycle); n represents an integer of 0 to 5; |