| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6291223cb0754d524a5f6d760cd8ed76 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-03006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
| filingDate |
2000-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d58571c00d56eb40a8934e6b0dfa4a57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74e23bc0cc68a8d3a539486f52239ee1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_225ec5e9db37df60c2683fce35a5b01b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a49fe8f8e1d485b42101c13ac4e7c72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffffc36b09c771d8b71b47c43fcd9089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d38a94a8911aec1532a8b59bf99365e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04cb18dba85c22f4a95e53855f1d90a0 |
| publicationDate |
2001-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20010066967-A |
| titleOfInvention |
Angiogenesis Inhibitor containing Arginine Deiminase |
| abstract |
The present invention relates to an angiogenesis inhibitor comprising an arginine diimide as an active ingredient, and more specifically, to angiogenesis inhibitory experiments such as capillaries using human vascular endothelial cells (HUVEC) and phosphorus angiogenesis inhibitory efficacy. Arginine diimides purified from Mycoplasma arginini or prepared by genetic recombination using an in vivo assay (CAM) assay and mouse matrigel model It has been shown to have an action to inhibit angiogenesis. In addition, by binding an activated polymer such as polyethylene glycol (PEG) to the prepared arginine diimides has been proposed a method that can effectively inhibit angiogenesis while increasing half-life and antigenicity. |
| priorityDate |
1999-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |