| abstract |
The present invention provides compounds of formula (I), and protein tyrosine kinase enzyme inhibitors such as Janus kinase 3 and organ transplantation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, type I diabetes and diabetes, cancer, asthma, atopic dermatitis, autologous A therapeutic method useful as an immunosuppressive agent for diseases selected from the group consisting of immune thyroid disease, ulcerative colitis, Crohn's disease, Alzheimer's disease, leukemia and other autoimmune diseases:n n n Formula In n n n n n n n Wheren n n R 1 , R 2 and R 3 are as defined in claim 1 of the claims. |