| abstract |
The present invention relates to (a) (-)-cis-6-phenyl-5- [4- (2-pyrrolidin-1-yl-ethoxy) -phenyl] -5,6,7,8-tetrahydronaphthalene -2-ol or a pharmaceutically acceptable salt thereof and (b) 2-amino-N- (1 (R)-(2,4-difluoro-benzyloxymethyl) -2-oxo-2- (3 -Oxo-3a (R) -pyridin-2-ylmethyl) -2- (2,2,2-trifluoro-ethyl) -2,3,3a, 4,6,7-hexahydro-pyrazolo [ 4,3-c] pyridin-5-yl) -ethyl) -2-methyl-propionamide or a pharmaceutically acceptable salt thereof, a method for using the composition, and a method for using the composition It relates to a kit containing. The composition is useful for the treatment of musculoskeletal tenderness, including osteoporosis, osteoporotic fractures, bone mass loss, erosion, and muscle mass loss. |