| abstract |
Tetrahydro-4- [3- (4-fluorophenyl) thio] phenyl-2H-pyran-4-carboxamiden n n n n n n n -And-n n n Chemical formulan n n n n n n n n n n A reaction mixture consisting of an electron deficient monocyclic or benzo-fused bicyclic N-heterocyclic ring containing two nitrogen atoms of (M) 2 -CO 3 in an aprotic solvent, wherein M is lithium, Li; Sodium, Na; Potassium, K; Rubidium, Rb; Cesium, Cs; an alkali metal of Group 1 / Ia element selected from the group consisting of; Then heating the reaction mixture under a nitrogen atmosphere to produce the desired compound of formulan n n Chemical formulan n n n n n n n In the method for producing a 5-lipoxygenase inhibitorn n n Chemical formulan n n n n n n n We describe the use of tetrahydro-4- [3- (4-fluorophenyl) thio] phenyl-2H-pyran-4-carboxamide as an intermediate of the novel process intermediates. |