| abstract |
The present invention relates to a penetration enhancer / solvent selected from the group consisting of (A) alcohols, propylene glycol, or combinations thereof, (B) polyethylene glycol, glycerin, sorbitol, xylitol, or any thereof Anhydrous compositions are provided for topical delivery of a medicament comprising a humectant / solvent selected from the group consisting of a combination, and (C) an anhydrous vehicle. In another embodiment, the present invention provides a permeation enhancer / solvent selected from the group consisting of (A) alcohols, propylene glycol, or combinations thereof, (B) polyethylene glycol, glycerin, sorbitol, xylitol Wetting agents / solvents selected from the group consisting of: or any combination thereof, (C) an anhydrous vehicle; And (D) anhydrous compositions for topical delivery of a medicament comprising a medicament. Also provided is a method of topically delivering a medicament by topically administering the composition of the present invention to an animal, such as a mammal or a patient in need thereof. |