Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
filingDate |
1998-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2001-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20010032687-A |
titleOfInvention |
Conjugates useful in the treatment of prostate cancer |
abstract |
Described herein are chemical conjugates comprising an oligopeptide having an amino acid sequence that is selectively and proteolytically cleaved by a free prostate specific antigen (PSA) and a known cytotoxic agent. The conjugates of the invention are characterized in that the cleavable oligopeptide is attached to an oxygen atom at the 4-position on the deacetylated vinca drug. Such conjugates are useful for treating prostate cancer and benign prostatic hyperplasia (BPH). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7842581-B2 |
priorityDate |
1997-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |