http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20010031297-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 |
| filingDate | 1998-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20010031297-A |
| titleOfInvention | 2-Substituted 1,2-Benzisothiazole Derivatives and Their Use as Serotonin Antagonists (5-HT1A, 5-HT1B and 5-HT1D) |
| abstract | The present invention relates to a 2-substituted 1,2-benzisothiazole derivative represented by formula (I). The present invention also relates to the preparation of the novel derivatives and their use as serotonin antagonists.n n n <Formula I>n n n n n n n n Wheren n n R 1 and R 2 independently of one another represent (C 1-6 ) alkyl,n n n A is branched or unbranched (C 1-10 ) -alkylene, or straight or branched (C 2-10 ) -alkylene, which is O, S, NR 7 , cyclopropyl, CHOH, double or At least one Z group selected from triple bonds,n n n B contains the N-atoms of 4-piperidine, 4-tetrahydro-1,2,3,6-pyridine, 4-piperazine, and B linked to A, and corresponding ring compounds having a larger methylene group Indicate,n n n Ar is optionally (C 1-6 ) alkyl branched or unbranched, O- (C 1-6 ) -alkyl branched or unbranched, OH, F, Cl, Br, I, trifluoromethyl , NR 5 R 6 , CO 2 R 7 , phenyl substituted with cyano or phenyl, tetralin, indane, optionally naphthalene substituted with (C 1-4 ) alkyl or O (C 1-4 ) alkyl; 5- or 6-membered aromatic heterocyclenes such as quinoline, isoquinoline, phthalazine, and quinazoline, including one or two heteroatoms independently selected from one another such as fused aromatic, anthracene, or O and N (Which itself may be substituted by phenyl and may be substituted by other aromatic groups),n n n R 3 and R 4 represent those described herein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7217436-B2 |
| priorityDate | 1997-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 249.