abstract |
The present invention is formula (I)n n n [Formula I]n n n n n n n n [Wherein R is an expressionn n n n n n n n , X represents O or S, and R 1 , R 2 , R 3 , R 4 , R 5, and R 6 have the meaning described in claim 1 of the claims.] Novel compounds or tautomers It relates to the sex ring. The invention also relates to the (E) isomer and salts thereof. The novel derivatives show endothelin receptor antagonism. |