| abstract |
The coated implantable medical device 10 of the present invention comprises a structure 12 suitable for introduction into a vascular system, esophagus, trachea, retardation, bile duct, urinary tract; At least one coating layer (16) located on the surface of one of the structures; At least one layer of biofunctional material located over at least a portion of the coating layer, wherein the coating layer 16 is provided for controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 may be located above the biomaterial layer 18, wherein the porous layer comprises a polymer, where it is provided for controlled release of the biomaterial. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer that is well applied by deposition or plasma deposition, and provides controlled release of bioactive materials. In particular the polymer is a polyamide, parylene or parylene derivative which is deposited only by condensation of the monomer vapor without solvents, heat or catalyst. |