| abstract |
The present invention relates to a method for inhibiting matrix metalloproteinases using a compound which is a dibenzofuran sulfonamide derivative having formula (I). More particularly, the present invention relates to multiple sclerosis, atherosclerotic plaque rupture, restenosis, aortic aneurysm, heart failure, periodontal disease, corneal ulcer, burns, pressure sores, chronic ulcers or wounds, cancer metastasis, tumor angiogenesis, arthritis or leukocytes The present invention relates to a method for treating a disease involving matrix metalloproteinases such as other autoimmune or inflammatory diseases following tissue invasion.n n n <Formula I> |