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filingDate 2000-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cfd4db9bb3cc1d66387ec205dca0c3a
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publicationDate 2000-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20000058125-A
titleOfInvention A process of manufacturing cycloalkenylpolyene esters
abstract The present invention is a process for producing the retinyl acylate of the formula (I), characterized in that the compound of formula (II) is treated with an acid anhydride or a complex of sulfur trioxide, as described in the presence of dimethylformamide as a solvent and weak base It is about:n n n n n n n n n n n n n n n n n Wheren n n R 1 is optionally substituted C 1-23 alkyl; C 2-23 alkenyl characterized by 1 to 5 double bonds; Phenyl-C 1-6 alkyl optionally substituted with aromatics; Or optionally substituted phenyl;n n n R 2 represents hydrogen or COR 1 .n n n In addition to dimethylformamide, an aprotic organic solvent may optionally be present, specifically aliphatic hydrocarbons, optionally alkyl-substituted alicyclic hydrocarbons, aromatic hydrocarbons, halogenated aliphatic hydrocarbons, nitrated aliphatic hydrocarbons, aliphatic ethers, Cyclic ethers, aliphatic nitriles, aliphatic amines, aliphatic or cycloaliphatic amides, dimethyl sulfoxide, tetramethylene sulfone, or mixtures of one or more such solvents. The product is useful as an intermediate for the preparation of compounds of the vitamin A group or in certain cases as the compound itself.
priorityDate 1999-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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