http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000057647-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 |
filingDate | 1997-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec95c1dee0c1aa5801ea7cf2d4349da8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c45af64b6b4734a4ba51e00f785df4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b08bc208d16e82eafa4bd330a54c6de9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4b6e9a35c278deedf4b7f6627d0d128 |
publicationDate | 2000-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20000057647-A |
titleOfInvention | Vaccine for the reversible immunocastration of mammals |
abstract | The present invention belongs to genetic engineering and biotechnology, and more particularly relates to the use of peptides derived from GnRH for immunocastration in mammals. Vaccination was performed in mammals to trigger an immune response that neutralizes the activity of gonadotropin releasing hormone (GnRH). The present invention relates to the use of GnRH variants in mammals, wherein the glycine residue at position 6 is substituted with proline: Glu-His-Trp-Ser-Tyr-Pro-Leu-Arg-Pro-Gly. The substitution or change induced a superior immune response when tested in pigs compared to native GnRH, and the same results are expected in other mammals because the hormone is present in all species. |
priorityDate | 1996-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.