| abstract |
The compound of formula 1, or a pharmaceutically or veterinary or agriculturally acceptable salt thereof, or a pharmaceutically or veterinary or agriculturally acceptable salt thereof, is an antiparasitic agent:n n n Formula 1n n n n n n n n Wheren n n R 1 is 2,4,6-trisubstituted phenyl or 3,5-disubstituted pyridin-2-yl;n n n R 3 is C 1 -C 4 alkyl which may be substituted with hydroxy or one or more halo; Cyano, C 1 -C 5 alkanoyl or phenyl;n n n R 5 is hydrogen, C 1 -C 4 alkyl, amino or halo;n n n R 2 and R 4 are each independently selected from hydrogen, C 1 -C 4 alkyl, fluoro, chloro and bromo or together with the carbon atom to which they are attached form a C 3 -C 6 cycloalkyl group;n n n R 6 and R 8 are each independently selected from hydrogen, C 1 -C 4 alkyl, fluoro, chloro and bromo;n n n If R 2 and R 4 do not form part of a cycloalkyl group, R 2 and R 6 together with the carbon atom to which they are attached may form a C 5 -C 7 cycloalkyl group;n n n R 7 is hydrogen, C 1 -C 4 alkyl which may be substituted with one or more halo, or C 1 -C 4 alkoxy. |