http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000056470-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16b7681084c49948d56f4d9beb316f34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a11b66ee4789438f60fb63b38cbeda7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cad273995f24737f38bb75d0063d4c3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B63-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B63-00 |
| filingDate | 1999-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_756e5d51b0480637210b8bfa753b91ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e483fe18c4039a825cfd5c143d13445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b263dcf6f5e9218b3b884f0ad78256b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a5153506d00afc411d74d660f95ea6 |
| publicationDate | 2000-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20000056470-A |
| titleOfInvention | Process for preparative resolution of metoprolol enantiomer |
| abstract | The present invention relates to a method for preparing a metoprolol enantiomer from a metoprolol racemate, specifically 1) by adding an optical isomerization reagent MCF (menthyl chloroformate) to the metoprolol racemate (± Obtaining) -diastereomers; 2) separating the (±) -diestereomeric mixture into (+), (-)-diestereomers using high performance liquid chromatography (HPLC); 3) hydrolyzing the separated (+) and (-)-diesteromers to obtain enantiomers, and racemization as compared to conventional asymmetric synthesis or chiral chromatography. It is a method that can economically obtain high purity metoprolol enantiomer in a simple and fast manner as well as showing a high yield without racemization. |
| priorityDate | 1999-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.