http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000049195-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_158979d400c8fe1ec2ea93ccf776a3d5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 |
| filingDate | 1997-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_799ac3634a3bb544b1d71175957c3bc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd5a256cc68b0011d67c6075cf6a5802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cce6a0a052a9c951e88c63b7baf56b76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7453f3cbe8928a4384ed6496e22fa0ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12e0a816976673890ce45c28a9129b71 |
| publicationDate | 2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20000049195-A |
| titleOfInvention | Process for preparing 2-azadihydroxybicyclo[2.2.1]heptane compounds and the l-tartaric acid salt of the compound |
| abstract | The process according to the invention comprises the following compounds of formula (III) or (III ') bicyclo [2.2.1] heptene, from about 0.1 to about 5 mol% of a metal osmate compound or from about 0.06 to about 0.07 mol% of A method for the preparation of 2-azadihydroxybicyclo [2.2.1.] Heptane compounds of the formulas (I) and (I '), comprising bishydroxylation in the presence of an oxidizing agent capable of regenerating osmium.n n n Formula In n n n n n n n Formula I 'n n n n n n n n Formula IIIn n n n n n n n Formula III 'n n n n n n n n Wheren n n * Represents R chirality,n n n * 'Represents S chirality,n n n R represents hydrogen or a group of the following formula (II) or (II ′), respectively.n n n Formula IIn n n n n n n n Formula II 'n n n n n n n n Wheren n n R 1 is alkyl,n n n Ar is optionally substituted aryl.n n n The invention also provides a process for treating (1R) diastereomers of 2-azadihydroxybicyclo [2.2.1] heptane compounds of formula I, wherein R is a group of formula II with L-tartaric acid, and thus L-tartaric acid. It relates to salt products. The present invention also provides the use of (1R) diastereomers of 2-azadihydroxybicyclo [2.2.1] heptane compounds in acid-promoted acetalization or ketalization reactions to protect their dihydroxy residues in isopropanol. do. The present invention also provides an O-protected derivative of the (1R) diastereomer of the 2-azadihydroxybicyclo [2.2.1] heptane compound in the presence of about 0.01 to about 1 mol% RuO 2 or a hydrate thereof. It also relates to a method of oxidizing with three equivalents of an oxidizing agent to produce a lactam compound having an enantiomeric excess of at least about 95%. |
| priorityDate | 1996-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.