| abstract |
Compounds of formula (I).n n n Formula In n n n n n n n Wherein X represents a hydrogen atom or a halogen atom or an alkyl, alkoxy, trifluoromethyl or phenylmethoxy group, R 1 represents a hydrogen atom or an alkyl, cyclopropyl or phenylmethyl group, and R 2 is optionally substituted Alkyl group or optionally substituted phenylalkyl group or cyclohexylmethyl group or thienylmethyl group or pyridinylmethyl group or optionally substituted phenyl group or pyridinyl group or 5-methyl-1,2-oxazolyl group or 5-methyl-1,3 , 4-thiadiazolyl group or naphthyl group, R 3 and R 4 each represent a hydrogen atom, an alkyl, 2-methoxyethyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl or phenylalkyl group, or Optionally substituted pyrrolidinyl or piperidinyl or morpholinyl or 4-methylpiperazinyl or azetidinyl or thia Piperidinyl, and the bond between 3 and 4-position of the carbon atom, form a is a single bond or a double bond)n n n Application to therapy. |