http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000048496-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
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filingDate 1997-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c110a8c19f6d141b83e015dba8cd54a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_774f04fcc238c429f0cd1409af694989
publicationDate 2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20000048496-A
titleOfInvention A crystalline substance of cefditoren pivoxyl and the production of the same
abstract As a novel material, there is provided a novel crystalline material of ceftitorene coating chamber having high purity and improved thermal stability upon storage. The crystalline ceftitorene coating chamber is prepared by dissolving the amorphous material in an anhydrous first organic solvent capable of sufficiently dissolving the ceftitorene coating chamber amorphous material, and the first organic solvent component of the solution thus obtained is subjected to a second step. Substituted with anhydrous alkanol having 1 to 5 carbon atoms as an organic solvent, the first organic solvent solution of the ceftitorene coating chamber prepared at the time of the solvent substitution was mixed with a predetermined amount of alkanol, and then the temperature was 15 ° C. or lower. It can be prepared by a method comprising the step of performing the solvent replacement by a method such as concentration in. By the solvent substitution step, a method is performed in which a solution containing 50 mg / ml to 250 mg / ml ceftitorene coating chamber dissolved only in alkanol is produced. The ceftitorene coating chamber crystal is precipitated by adding water from the latter alkanol solution at a temperature of 0 to 10 ° C. Next, a mixture of the concentrated solution of the ceftitorene coating chamber dissolved in the alkanol thus obtained, the added water, and the precipitated material of the ceftitorene coating chamber was stirred at 10 ° C. or lower to crystallize the ceftitorene coating chamber. To complete.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014189308-A1
priorityDate 1996-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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