http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000036017-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d779d73c301192ffbaf00434e582a534 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
filingDate | 1997-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34fe8bebeefb7c4537be5a664bd93123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dda082f51fb66d265c2a198abb9f44c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f43fc03a36d11bde5628f657c8cd3c7e |
publicationDate | 2000-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20000036017-A |
titleOfInvention | Benzamidine Derivatives Substituted by Cyclic Amino Acid and Cyclic Hydroxy Acid Derivatives and Their Use as Anti-Coagulants |
abstract | The present invention provides cyclic amino acids and cyclic hydroxy acids useful as anticoagulants represented by the following formulas (I), (II), (III), (IV), (V), (VI) and (VII) It relates to a benzamidine derivative substituted with a derivative.n n n <Formula (I)>n n n n n n n n <Formula (II)>n n n n n n n n <Formula (III)>n n n n n n n n <Formula (IV)>n n n n n n n n <Formula (V)>n n n n n n n n <Formula (VI)>n n n n n n n n <Formula (VII)>n n n n n n n n In the above formula,n n n A is -C (R 8 ) = or -N =;n n n Z 1 and Z 2 are independently —O—, —N (R 9 ) —, —S—, —S (O) —, —S (O) 2 —, or —OCH 2 —;n n n R 2 is -C (NH) NH 2 , -C (NH) N (H) OR 9 , -C (NH) N (H) C (O) R 12 , -C (NH) N (H) C ( O) R 9 , C (NH) N (H) S (O) 2 R 12 or -C (NH) N (H) C (O) N (H) R 9 ;n n n R 7 is -N (R 9 )-(C (R 9 ) (R 10 )) n -R 13 (where n is 0 to 4), or -OC (R 9 ) (R 10 )) n- R 13 , where n is 0 to 4, or —N (R 14 ) R 15 ;n n n R 1 and R 3 to R 6 are as defined in the above description. The present invention further relates to pharmaceutical compositions containing the compounds of the invention and to methods of using said compounds in methods of treating disease states having characteristics of thrombotic activity. |
priorityDate | 1996-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 480.