| abstract |
Provided are novel anti-edemas, edema inhibitors, and vascular permeable anti-inflammatory agents of the blood brain barrier with little side effects and high stability.n n n The present invention provides novel anti-edema, edema-inhibiting agent and vascular permeability-inhibiting agent of blood brain barrier, which contain histamine-immunoglobulin as an active ingredient.n n n The pharmaceutical composition of the present invention inhibits vascular permeability of the blood brain barrier and also suppresses edema formation. Histamine-immunoglobulin, an active ingredient of the pharmaceutical composition of the present invention, is known to have a low incidence of side effects. Therefore, the pharmaceutical composition of the present invention is a novel high-efficacy anti-edema, edema-inhibiting agent, and anti-vascular permeability inhibitor of blood brain barrier. useful. |