| abstract |
The present invention relates to an angiotensin II receptor binding inhibitor isolated from sewage oil and a method for preparing the same, and more particularly, an angiotensin II receptor binding inhibitor composed of a compound represented by the following formula (1), a derivative thereof or a salt thereof, and an organic solvent extraction and The present invention relates to a method for preparing an angiotensin II receptor binding inhibitor from sewage oil by various chromatography, wherein the angiotensin II receptor binding inhibitor of the present invention is excellent in angiotensin II receptor binding inhibitory activity and antagonizes angiotensin II-induced vasoconstriction. Because of its excellent action, it can be used for diseases related to angiotensin II, namely hypertension, arteriosclerosis, cardiovascular thickening, and kidney diseases such as congestive heart failure and diabetic nephropathy.n n n Formula 1n n n n n n n n In Formula 1, R represents an aliphatic group having 5 to 20 carbon atoms. |