abstract |
The present specification describes steroid compounds having various oxygen substituents in the steroid nucleus. Particular functional groups present in many of these steroid compounds are oxygen substituents at both the 6 and 7 positions. Thus, certain steroids have oxygen substituents on C6 and C7 and some have specific stereochemistry such as 6α and 7β oxygen substitutions and alpha hydrogen at position 5 in addition to 6α and 7β oxygen substitutions. Steroids with 3,4-epoxy functional groups are also described. Also described are steroids with C17 pyrans and δ-lactone functional groups, with oxygen substituents on C6 and C7, or C15 of the steroid nucleus. |