| abstract |
A compound of formula (I) or a salt thereof or a solvate thereof, a process for preparing the compound, a pharmaceutical composition containing the compound, and use of the compound in a medicament.n n n <Formula I>n n n n n n n n Wheren n n R a represents a R 5 group which is hydrogen, alkyl or optionally substituted aryl,n n n R b represents a residue of formula a,n n n <Formula a>n n n n n n n n (Whereinn n n X is a hydroxy, an alkoxy group wherein the alkyl group is optionally substituted or unsubstituted, or an NR s R t group, where R s and R t are each independently hydrogen, alkyl, substituted alkyl, optionally substituted alkenyl, optionally substituted Aryl, optionally substituted arylalkyl, optionally substituted heterocyclic group or optionally substituted heterocyclylalkyl group, or together with the nitrogen to which they are attached to form a heterocyclic group); R 1 represents an alkyl or substituted or unsubstituted aryl group; R 2 , R 3 and R 4 each independently represent hydrogen, alkyl, aryl or substituted aryl)n n n R 6 and R 7 are each independently hydrogen, hydroxy, amino, alkoxy, optionally substituted aryloxy, optionally substituted benzyloxy, alkylamino, dialkylamino, halo, trifluoromethyl, trifluoromethoxy, nitro , Alkyl, carboxy, carboalkoxy, carbamoyl, alkylcarbamoyl, or together represent methylenedioxy, carbonyldioxy or carbonyldiamino,n n n R 8 represents hydrogen, hydroxy, alkanoyl, alkyl, aminoalkyl, hydroxyalkyl, carboxyalkyl, carvalkoxyalkyl, carbamoyl or aminosulfonyl. |