http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000022107-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1fc80f00a0875f919861004dc505f9d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-02 |
| filingDate | 1998-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82a17c7cae5ed8fb557cbd02cb9b9c57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_994b7400e5f1eb88c42b77f2b9efc4d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddbb3aea37ab857bf1254d394baa941c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07f567723d510911faad90be14d420f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35ce6106ec204daa19717a3d40a9040a |
| publicationDate | 2000-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20000022107-A |
| titleOfInvention | Improved Fermentation Method for Cephalosporins |
| abstract | The present invention fermentation of cephalosporin-producing microorganisms in the presence of a side chain precursor, extracting the N-substituted cephalosporin compound in the fermentation broth with an organic solvent, and back-extracting the N-substituted cephalosporin compound with water, Is a novel process for the preparation of deacylated cephalosporins at 7-amino groups by treating with a dicarboxylate acylase and separating the crystalline cephalosporin compound according to formula (I) from the conversion solution. Before the fermentation broth extract or before further treatment of the reverse extract relates to a production method characterized in that the culture in the acidic conditions and elevated temperature. Another improvement of the method is obtained by washing the first organic solvent extract with acidic water or extracting the side chain with an organic solvent or treating the aqueous cephalosporin solution prepared in one or more steps of the process with carbon dioxide. |
| priorityDate | 1997-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.