http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20000022106-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e83d93ed02bbd6159e99b5a7796e3686 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 |
| filingDate | 1998-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8f824b73d60328f529da7cdeee75d35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_995055086975c35ae8ddd9a2be9f0e5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de9d60775f55f8dafad5f1ede54c32d9 |
| publicationDate | 2000-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20000022106-A |
| titleOfInvention | Method for preparing β-lactam antibiotics |
| abstract | The present invention relates to a process for preparing β-lactam antibiotics, wherein the N-substituted β-lactam or a salt thereof having the formula (I) is contacted with at least one dicarboxylate acyla or functional equivalent thereof: And react with precursors to the side chains of β-lactam antibiotics in the presence of at least one penicillin acylase or functional equivalent thereof:n n n Formula In n n n n n n n In the above formula,n n n R 0 is hydrogen or C 1-3 alkoxy; Y is the oxidation form of CH 2 , oxygen, sulfur or sulfur; Z is the following (a), (b), (c) and (d)n n n n n n n n Wherein R 1 is hydrogen, hydroxy, halogen, C 1-3 alkoxy, saturated or unsaturated, branched or straight chain C 1-5 alkyl, preferably methyl, optionally substituted with one or more optionally containing one or more heteroatoms C 5-8 cycloalkyl substituted, optionally containing one or more heteroatoms, optionally substituted aryl or heteroaryl, or optionally substituted benzyl; And X is (CH 2 ) m -A- (CH 2 ) n , where m and n are the same or different and are selected from the group of integers 0, 1, 2, 3 or 4, and A is CH = CH, C ≡C, CHB, C═O, optionally oxidized form of optionally substituted nitrogen, oxygen, sulfur or sulfur, and B is hydrogen, halogen, hydroxy, C 1-3 alkoxy or optionally substituted methyl. |
| priorityDate | 1997-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.