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filingDate 1997-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e131ac5834000de7dd078e5df0479f9
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publicationDate 2000-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20000016807-A
titleOfInvention Quinolonecarboxylic acid substituted by 7- (3-vinyl-1,4-piperazin-1-yl)
abstract The present invention relates to novel 7- (3-vinyl-1,4-piperazin-1-yl) -substituted quinolonecarboxylic acids of the general formula (I), their preparation and their use in antibacterial agents.n n n n n n n n Wheren n n R 1 is hydrogen, optionally hydroxyl-, methoxy-, amino-, methylamino- or dimethylamino-substituted alkyl of 1 to 4 carbon atoms or (5-methyl-2-oxo-1,3-dioxol- 4-yl) -methyl;n n n R 2 represents hydrogen or fluorine (in this case R 4 is not hydrogen or fluorine at the same time), amino, methyl or vinyl,n n n R 3 is hydrogen, benzyl, alkyl of 1 to 3 carbon atoms, -CH = CH-COOR 5 , -CH 2 CH 2 -COOR 5 , -CH 2 CH 2 CN, -CH 2 CH 2 COCH 3 or -CH A radical of 2 COCH 3 , wherein R 5 represents methyl or ethyl, or a radical of the formula R 6 — (NH—CHR 7 —CO) n −, wherein R 6 is hydrogen, 1 to carbon atoms; Alkyl or radicals —COO-t-butyl of 3, R 7 represents hydrogen, alkyl of 1 to 4 carbon atoms, hydroxyalkyl of 1 or 2 carbon atoms, CH 2 -phenyl, aminoalkyl or 1 or 2 carbon atoms Thioalkyl of which n is 1 or 2), andn n n R 4 represents hydrogen or fluorine, in which case R 2 represents amino, methyl or vinyl, or chlorine, methoxy, difluoromethoxy, CN or ethynyl.
priorityDate 1996-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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